Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non-randomised, uncontrolled, phase 1 trial

The study aimed to assess the safety and immunogenicity of the candidate simian adenovirus-vectored vaccine ChAdOx1 MERS, in humans.ChAdOx1 MERS was safe and well tolerated at all tested doses. A single dose was able to elicit both humoral and cellular responses against MERS-CoV. The Lancet Infectious Diseases

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