Factors influencing diagnosis and treatment initiation for multidrugresistant/rifampicin-resistant tuberculosis in six sub-Saharan African countries: a mixed-methods systematic review

Jul 06, 2020

The review identified barriers and facilitators influencing diagnosis and treatment for drugresistant tuberculosis (DR-TB) in sub- Saharan Africa. Laboratory operational challenges as well as inadequate healthcare worker knowledge, attitude and skills were the predominant barriers noted at the health system level. Predominant patient-level barriers included loss to follow-up and death, as well as inability to pay carerelated costs.  Availability of newer diagnostic tools was the predominant health-level facilitator of quicker diagnosis and treatment; however, this did not always translate to significantly higher rates of diagnosis and treatment. BMJ Global Health

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