Movement of St. Louis encephalitis virus in the Western United States, 2014- 2018

St. Louis encephalitis virus (SLEV) is a flavivirus that circulates in an enzootic cycle between birds and mosquitoes and can also infect humans to cause febrile disease and sometimes encephalitis. hree routes of SLEV dispersal in the western United States were identified: Arizona to southern California, Arizona to Central California, and Arizona to all locations east of the Sierra Nevada mountains. Genetic tracing suggests that all SLEV activity since 2015 in central California is the result of a single persistent SLEV introduction. PLOS Neglected Tropical Diseases

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