Evaluating the validity of dengue clinical-epidemiological criteria for diagnosis in patients residing in a Brazilian endemic area

There are substantial variation in sensitivity, specificity, PPV and NPV of dengue signs and symptoms. For accuracy, clinical and laboratory diagnosis of dengue should be performed concurrently. When laboratory tests are not available, researchers suggest focusing on the clinical manifestations most associated with dengue. Transactions of The Royal Society of Tropical Medicine and Hygiene

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