‘Designer Virus’ is First New Polio Vaccine in 50 Years

The results of the phase 1 clinical trial found that the new designer polio vaccine was both more stable and more effective than the 50-year old Sabin vaccine from which it was derived. Specifically, the new vaccine caused participants to generate plentiful antibodies against the poliovirus, and despite shedding viral particles in their stool, those particles were unable to infect or cause paralysis in mice. University of California San Francisco

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