Notes from the Field: Intestinal Colonization and Possible Iatrogenic Botulism in Mouse Bioassay-Negative Serum Specimens --- Los Angeles County, California, November 2017

Mouse bioassay is the standard test for botulinum neurotoxin detection. However, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry testing can be 10-100 times more sensitive than MBA but is not yet widely available.

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