New CDC Guidelines Recommend Doxy PEP to Prevent Bacterial STIs

Published on June 7, 2024

The CDC finalized new guidelines that recommend doxycycline post-exposure prophylaxis (doxy PEP) for at-risk gay, bisexual, and other men who have sex with men (MSM) and transgender women (TGW) to prevent bacterial sexually transmitted infections (STIs).

Healthcare providers should discuss and offer doxy PEP to people in these populations with a history of at least one bacterial STI -- specifically syphilis, chlamydia, gonorrhea -- in the last 12 months, Lindley Barbee, MD, of the CDC's National Center for HIV, Viral Hepatitis, STD, and TB Prevention, and colleagues wrote in Morbidity and Mortality Weekly Report.

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